International Journal of Current Research in Physiology and Pharmacology (IJCRPP) 2019-11-18T13:52:03-05:00 IJCRPP, Sumathi Publications Open Journal Systems <p><strong>eISSN: 2523-6709,&nbsp;</strong><strong>pISSN: 2523-6695.</strong></p> <p style="text-align: left;">(Logos are embedded with links)</p> <hr> <p style="text-align: left;"><a href=";refid=dcrecen" target="_blank" rel="noopener"><img src="/public/site/images/admin/base.png" alt=""></a> <a href=";publication=International+Journal+of+Clinical+and+Biomedical+Research&amp;publisher_str=Sumathi+Publications&amp;type=Journal+Article" target="_blank" rel="noopener"><img src="/public/site/images/admin/crossref1.png" alt=""></a> <a title="IJCRPP" href=";as_sdt=0%2C5&amp;;oq=site" target="_blank" rel="noopener"><img src="/public/site/images/admin/GoogleScholar1.png" alt=""></a> <a href=";qt=results_page" target="_blank" rel="noopener"><img src="/public/site/images/admin/logo_wcmasthead_en1.png" alt=""></a> <a href="" target="_blank" rel="noopener"><img src="/public/site/images/admin/pkp-index-301.png" alt=""></a> <a href=";la=en" target="_blank" rel="noopener"><img src="/public/site/images/admin/sherparomeo-home.jpg" alt=""></a></p> <hr> <p>International Journal of Current Research in Physiology and Pharmacology (IJCRPP) provides an outlet for research scientists in areas of Health Sciences. IJCRPP is open access, online &amp; Print, peer-reviewed international journal with a primary objective to provide research and applications related to Physiology, Pharmacology and Clinical Medicine.</p> <p>Submitted papers must be in technical English, suitable for scientific publication. All articles have to be original articles that have not been published elsewhere or are being considered for publication in other journals. All articles submitted will be peer-reviewed by experts. Receipt of the manuscript will be acknowledged by email. Every effort will be made to complete the review process within 3 weeks and communicated to the corresponding author. Papers should be submitted electronically on the journal's website. The Editorial Board will strive for the quality of the journal and will also index the journal in various indexing bodies and the information will be updated on the journal website from time to time.</p> <p>We welcome all your submissions.</p> <p>I hope you will consider IJCRPP for your next submission.</p> <p>If any further information is required please mail to:</p> <p><a href="" target="_blank" rel="noopener"></a> or</p> <p><a href="" target="_blank" rel="noopener"></a>.</p> <p>The journal accepts manuscripts in the following forms:</p> <ul> <li class="show">Original research articles</li> <li class="show">Reviews</li> <li class="show">Case reports</li> <li class="show">Short communications</li> <li class="show">Letters to editor</li> <li class="show">Discussion papers</li> <li class="show">Clinical Experience</li> <li class="show">Clinicopathological correlation</li> <li class="show">Book reviews</li> <li class="show">"How to do it" type articles describing new methods or procedures.</li> </ul> <p>Aim :</p> <ul> <li class="show">Our goal is to stimulate new research ideas and foster practical application from the research findings. The journal publishes original research, review articles, case reports of such high quality as to attract contributions from the relevant international communities.</li> </ul> <p>Critical Objective:</p> <ol> <li class="show">To maintain the highest standards of editorial integrity</li> <li class="show">To improve health, health care, and health education, internationally by elevating the quality of medical care, disease prevention, and research</li> <li class="show">To publish original, important, well-documented, peer-reviewed articles on basic medical sciences subject topics</li> <li class="show">To provide doctors with continuing education in basic&nbsp; science to support clinical decisions</li> <li class="show">To enable physicians to remain informed in multiple areas of basic medical science, including developments In the field of health education.</li> <li class="show">To achieve the highest level of ethical medical journalism and to produce a publication that is timely, credible, and enjoyable to read.</li> </ol> <p>Kind Regards,</p> <p>IJCRPP Editorial Team.</p> Evaluating serum C-reactive protein level in patients with chronic obstructive pulmonary disease – A cross-sectional study 2019-11-18T13:52:03-05:00 Karthika M Prakash Chandra Bhardwaj Laimayum Amarnath Sharma Laimayum Amarnath Sharma W Kanan W Asoka Singh <p><strong>Abstract</strong></p> <p>Patients with the chronic obstructive pulmonary disease have ongoing systemic inflammation, which can be assessed by measuring serum&nbsp; C- reactive protein.</p> <p><strong>Objective</strong>: To explore whether CRP could be used as an independent predictor of disease outcome in COPD.</p> <p><strong>Methods</strong>: A cross-sectional study was conducted among 50 COPD patients attending Respiratory Medicine outpatient services in the Regional Institute of Medical Sciences (RIMS), Imphal from January 2015 to September 2016. Patients aged 18-67 were included in the study after obtaining Ethical approval from the Research Ethics Board, RIMS, Imphal. Computerized Spirometer Helios 401 was the instrument used to measure lung volumes and capacities. BeneSphera<sup>TM</sup> CRP Latex Slide test kit was used to estimate serum c-reactive protein.</p> <p><strong>Results </strong><strong>and observation</strong>: The present study was conducted on fifty COPD patients in which serum CRP level showed positive correlation with COPD (p=0.002) but serum CRP level with spirometric parameters showed significant negative correlation;FEV<sub>1</sub> (r=-0.451, p=0.001), FEV<sub>1</sub>/FVC (r=-0.617, p&lt;0.001) and PEFR (r=-0.398, p=0.004).</p> <p><strong>Conclusion</strong>: In our study, we found an association between serum CRP level and severity of COPD and Plasma CRP may be used as a marker of prognosis in COPD as the small increase is associated with poorer prognosis in COPD.</p> <p><strong>Keywords</strong>: CRP; Chronic obstructive pulmonary disease (COPD); Imphal.</p> 2019-10-31T00:00:00-04:00 ##submission.copyrightStatement## The potential effect of pandan wangi leaf “pandanus amaryllifolius roxb.’’ extract from Indonesia as time sleep inductor 2019-11-18T13:52:01-05:00 Nita Tri Sulistiyati Riandini Aisyah EM Sutrisna <p>Sleep plays a role in restoring the body's biochemical and physiological processes which decrease when awake. People is not familiar yet with sleep disturbances, so they rarely seek help. Sleep disturbances can cause family problems and are at risk of fatal traffic accidents. Fragant Pandan leaves (Pandanus amaryllifolius Roxb.) contains alkaloids, saponins and flavonoids which can provide a hypnotic sedative effect. The purpose of this study was to determine the effect of fragant Pandan leaf extract (Pandanus amaryllifolius Roxb.) administration in shortening the sleep induction time of male Swiss Webster strain mice. A post-test only design experimental laboratory study was conducted with control group design. The test animals used were 25 Swiss Webster male mice divided into five groups randomly : G1 group was given distilled water, G2 was given diazepam dose 1 mg / KgBB, the G3, G4 and G5 groups were given fragant Pandan leaf extract with a dose of 4 mg/25g BB, 6 mg/25g BB and 8mg/25g BB, respectively. One Way ANOVA statistical test showed significant differences in mice sleep onset (p=0.000) between groups. The results of the Post Hoc test using LSD analysis showed that there were significant differences between positive controls with groups G3, G4 and G5. Fragrant Pandan leaf extract dose of 8 mg/g BB can shorten the time of mice sleep induction male Swiss Webster strain mice. While the dose of 4 mg/g BB cannot shorten the time of induction of sleeping mice.</p> <p>Keywords: Fragant Pandan leaf extract; Hypnotic-sedative; Sleep disturbances.</p> 2019-10-31T00:00:00-04:00 ##submission.copyrightStatement## Public Health concern for a Nipah Virus disease 2019-11-18T13:52:02-05:00 Ajaykumar Rikhabchand Surana Manoj Ramesh Kumbhare Apurva Uttamrao Abhale Ankita Ankush Bhoir Shivam Puranmalgi Agrawal <p>Nipah virus (NiV) is a pathogenic paramyxovirus that has been responsible for sporadic outbreaks of respiratory and encephalitic disease in tropical countries. Elevated case mortality rate has also been connected with recent outbreaks in India (Kerala), Malaysia and Bangladesh. The virus generally infects animals like pigs and bats, but they do not show any symptoms of NiV.&nbsp; The mortality rate in NiV infected humans is more as compared to other mammals. The patient usually shows no symptoms to headache fever, cough, dyspnea, confusion and more consequences lead to a coma. Although there are no drugs or vaccines available against this severe disease, precaution and awareness reduce the risk of NiV-infection. This review will be helpful to save the life of people and decrease death by the NiV-infection outbreak.</p> <p><strong>Keywords</strong>:&nbsp; &nbsp;Diagnosis, Henipavirus, Nipah virus, Prevention and treatment</p> 2019-10-31T00:00:00-04:00 ##submission.copyrightStatement## Role of Udvartana, a diurnal Ayurveda practice in the prevention and management of diabetes mellitus 2019-11-18T13:52:02-05:00 Aditya Bhat Geetha Kumari S <p>Diabetes is among the most common lifestyle disorders of the modern era. The current approach towards its prevention and management is largely based on diet and lifestyle modifications. As increased body weight and serum lipids have been implicated in the risk factors of diabetes, measures to reduce them have a significant role to play. Udvartana described as a diurnal practice for health maintenance in Ayurveda plays an important role in the prevention and management of diabetes. Clinical studies have shown that Udvartana helps in reducing body weight as well as serum lipids. A review of the role of Udvartana in the prevention and management of diabetes is attempted here.</p> <p><strong>Keywords</strong>: Diabetes; Udvartana; Body weight; Serum lipids.</p> 2019-10-31T00:00:00-04:00 ##submission.copyrightStatement##