International Journal of Clinical and Biomedical Research https://www.sumathipublications.com/index.php/ijcbr <p style="text-align: center;"><strong>ISSN: 2395-0471 (Online), </strong><strong>ISSN: 2521-0394 (Print).</strong></p> <p style="text-align: center;"><strong>Journal indexed in following major databases; Logos are embedded with respective links. Go to the Indexed in page for more indexing information</strong></p> <hr /> <p><a href="https://journals.indexcopernicus.com/search/journal/issue?issueId=all&amp;journalId=32442" target="_blank" rel="noopener"><img src="https://www.sumathipublications.com/public/site/images/admin/copernicus.jpg" alt="" width="115" height="32" /></a><a href="https://www.base-search.net/Search/Results?q=dccoll:ftsumathipubl&amp;refid=dcrecen" target="_blank" rel="noopener"><img src="https://www.sumathipublications.com/public/site/images/admin/base.png" alt="" width="74" height="35" /></a> <a href="https://scholar.google.co.in/scholar?start=0&amp;q=2395-0471&amp;hl=en&amp;as_sdt=0,5" target="_blank" rel="noopener"><img src="https://www.sumathipublications.com/public/site/images/admin/GoogleScholar1.png" alt="" width="74" height="28" /></a><a href="http://www.worldcat.org/search?q=ijcbr&amp;qt=results_page" target="_blank" rel="noopener"><img src="https://www.sumathipublications.com/public/site/images/admin/logo_wcmasthead_en1.png" alt="" width="102" height="32" /></a><a href="http://index.pkp.sfu.ca/index.php/browse/index/4035" target="_blank" rel="noopener"><img src="https://www.sumathipublications.com/public/site/images/admin/pkp-index-301.png" alt="" /></a><a href="https://v2.sherpa.ac.uk/id/publication/30542" target="_blank" rel="noopener"><img src="https://www.sumathipublications.com/public/site/images/admin/sherparomeo-home.jpg" alt="" /></a><a href="http://imsear.searo.who.int/handle/123456789/170455?subject_page=1" target="_blank" rel="noopener"><img src="https://www.sumathipublications.com/public/site/images/admin/rsz_21rsz_1rsz_imsear.png" alt="" width="141" height="30" /></a></p> <hr /> <p>International Journal of Clinical and Biomedical Research provides an outlet for research scientists in areas of Health Sciences. IJCBR is open access, online &amp; print, peer-reviewed international journal with a primary objective to provide research and applications related to all the health sciences:</p> <p>All branches of Biomedical Sciences,</p> <ul> <li class="show">Biology,</li> <li class="show">Dentistry,</li> <li class="show">Medical Education,</li> <li class="show">Physiotherapy,</li> <li class="show">Pharmacy, and Nursing.</li> </ul> <p>Submitted papers must be in technical English, suitable for scientific publication. All articles have to be original articles that have not been published elsewhere or are being considered for publication in other journals. All articles submitted will be peer-reviewed by experts. Receipt of the manuscript will be acknowledged by email. Every effort will be made to complete the review process within 3 weeks and communicated to the corresponding author. Papers should be submitted electronically on the journal's website. The Editorial Board will strive for the quality of the journal and will also index the journal in various indexing bodies and the information will be updated on the journal website from time to time. We welcome all your submissions. I hope you will consider IJCBR for your next submission. If any further information is required please mail to:</p> <p> <a href="http://localhost/sppp/index.php/index/admin/wizard/2/mailto:editor.ijcbr@gmail.com">Editor</a> and/or <a href="http://localhost/sppp/index.php/index/admin/wizard/2/mailto:journaloffice@sumathipublications.com">Journal Office</a>.</p> <p>The journal accepts manuscripts in the following forms:</p> <ul> <li class="show">Original research articles</li> <li class="show">Reviews</li> <li class="show">Case reports</li> <li class="show">Short communications</li> <li class="show">Letters to editor</li> <li class="show">Discussion papers</li> <li class="show">Clinical Experience</li> <li class="show">Clinicopathological correlation Book reviews and</li> <li class="show">"How to do it" type articles describing new methods or procedures.</li> </ul> <p>Kind regards,</p> <p>IJCBR Editorial Team.</p> en-US <p>The journal <strong>allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions</strong>.</p> <p>The submitted papers are assumed to contain no proprietary material unprotected by patent or patent application; responsibility for technical content and for protection of proprietary material rests solely with the author(s) and their organizations and is not the responsibility of the journal. The main (first/corresponding) author is responsible for ensuring that the article has been seen and approved by all the other authors. It is the responsibility of the author to obtain all necessary copyright release permissions for the use of any copyrighted materials in the manuscript prior to the submission.</p> <p><strong>What are my rights as an author?</strong><br>It is important to check the policy for the journal to which you are submitting or publishing to establish your rights as<br>Author. Journal's standard policies allow the following re-use rights:</p> <ul> <li class="show">The journal allows the author(s) to hold the copyright without restrictions.</li> <li class="show">The journal allows the author(s) to obtain publishing rights without restrictions.</li> <li class="show">You may do whatever you wish with the version of the article you submitted to the journal.</li> <li class="show">Once the article has been accepted for publication, you may post the accepted version of the article on your own personal website, your department's website or the repository of your institution without any restrictions.</li> <li class="show">You may not post the accepted version of the article in any repository other than those listed above (i.e. you may not deposit in the repository of another institution or a subject-matter repository) until 12 months after publication of the article in the journal.</li> <li class="show">You may use the published article for your own teaching needs or to supply on an individual basis to research colleagues, provided that such supply is not for commercial purposes.</li> </ul> editor@sumathipublications.com (Sumathi Publications) admin@sumathipublications.com (Admin) Wed, 10 May 2023 17:49:03 +0000 OJS 3.3.0.13 http://blogs.law.harvard.edu/tech/rss 60 Aflatoxins: An Innocent Cause of Lethality in Humans https://www.sumathipublications.com/index.php/ijcbr/article/view/457 <p>According to Food and Agriculture Organization, United Nations, approximately one-fourth of the world’s food crops are continuously being contaminated comprehensively by mycotoxins. More than 300 types of mycotoxins are produced by one-fourth of the cereal crops infected. The foodstuffs containing aflatoxins are indiscriminately being consumed by people developing various ailments, diseases and even cancer innocently. Aflatoxins (Afs) have been the most widely studied mycotoxin worldwide. The disease caused by the ingestion of aflatoxins is collectively called aflatoxicosis. They are mostly found in peanuts, mouldy maize grains, rice and perishable dairy products. There are four major types of aflatoxins (AFB<sub>1</sub>, AFB<sub>2</sub>, AFG<sub>1</sub> and AFG<sub>2</sub>) found in nature mainly produced by the <em>Aspergillus flavus, A. parasiticus </em>and<em> A. nomius</em>. Aflatoxin B<sub>1</sub> has always been a potent carcinogen classified by the WHO in Group “A” as causing cancer in humans. It induces mutation in the p53 gene to develop hepatocellular carcinoma (HCC) in humans. This is the third leading cause of cancer deaths worldwide. Keeping view in mind the present paper is an attempt to review the research done so far in the field of aflatoxins in humans. The review focuses on occurrence, epidemiology, historical glimpses, chemical nature and the types of aflatoxins, detection and detoxification, diagnosis, clinical symptoms and the treatment of aflatoxicosis in humans.</p> <p><strong data-id="_bold-2">Keyword</strong><strong data-id="_bold-3">s</strong><strong data-id="_bold-4">: </strong>Aflatoxins, Occurrence, Detection, Detoxification, Aflatoxicosis, AFB<sub data-id="_subscript-6">1,</sub>AFB<sub data-id="_subscript-7">2</sub>, AFG<sub data-id="_subscript-8">1 </sub>, AFG<sub data-id="_subscript-9">2</sub>, Hepatocellular Carcinoma</p> Mohammad Salim, Shafikun Nisha, Mohammad Shahid Masroor, Shagufta Parween Copyright (c) 2023 Mohammad Salim, Shafikun Nisha, Mohammad Shahid Masroor, Shagufta Parween http://creativecommons.org/licenses/by-nc-sa/4.0 https://www.sumathipublications.com/index.php/ijcbr/article/view/457 Wed, 10 May 2023 00:00:00 +0000