International Journal of Clinical and Biomedical Research https://www.sumathipublications.com/index.php/ijcbr <p style="text-align: center;"><strong>ISSN: 2395-0471 (Online), </strong><strong>ISSN: 2521-0394 (Print).</strong></p> <p style="text-align: center;"><strong>Journal indexed in following major databases; Logos are embedded with respective links. Go to the Indexed in page for more indexing information</strong></p> <hr /> <p><a href="https://journals.indexcopernicus.com/search/journal/issue?issueId=all&amp;journalId=32442" target="_blank" rel="noopener"><img src="https://www.archives.sp.oajour.info/public/site/images/admin/copernicus.jpg" alt="" width="115" height="32" /></a><a href="https://www.base-search.net/Search/Results?q=dccoll:ftsumathipubl&amp;refid=dcrecen" target="_blank" rel="noopener"><img src="https://www.archives.sp.oajour.info/public/site/images/admin/base.png" alt="" width="74" height="35" /></a> <a href="https://scholar.google.co.in/scholar?start=0&amp;q=2395-0471&amp;hl=en&amp;as_sdt=0,5" target="_blank" rel="noopener"><img src="https://www.archives.sp.oajour.info/public/site/images/admin/GoogleScholar1.png" alt="" width="74" height="28" /></a><a href="http://www.worldcat.org/search?q=ijcbr&amp;qt=results_page" target="_blank" rel="noopener"><img src="https://www.archives.sp.oajour.info/public/site/images/admin/logo_wcmasthead_en1.png" alt="" width="102" height="32" /></a><a href="http://index.pkp.sfu.ca/index.php/browse/index/4035" target="_blank" rel="noopener"><img src="https://www.archives.sp.oajour.info/public/site/images/admin/pkp-index-301.png" alt="" /></a><a href="http://www.sherpa.ac.uk/romeo/search.php?source=journal&amp;sourceid=30542&amp;la=en&amp;fIDnum=|&amp;mode=simple" target="_blank" rel="noopener"><img src="https://www.archives.sp.oajour.info/public/site/images/admin/sherparomeo-home.jpg" alt="" /></a><a href="http://imsear.searo.who.int/handle/123456789/170455?subject_page=1" target="_blank" rel="noopener"><img src="https://www.archives.sp.oajour.info/public/site/images/admin/rsz_21rsz_1rsz_imsear.png" alt="" width="141" height="30" /></a></p> <hr /> <p>International Journal of Clinical and Biomedical Research provides an outlet for research scientists in areas of Health Sciences. IJCBR is open access, online &amp; print, peer-reviewed international journal with a primary objective to provide research and applications related to all the health sciences:</p> <p>All branches of Biomedical Sciences,</p> <ul> <li class="show">Biology,</li> <li class="show">Dentistry,</li> <li class="show">Medical Education,</li> <li class="show">Physiotherapy,</li> <li class="show">Pharmacy, and Nursing.</li> </ul> <p>Submitted papers must be in technical English, suitable for scientific publication. All articles have to be original articles that have not been published elsewhere or are being considered for publication in other journals. All articles submitted will be peer-reviewed by experts. Receipt of the manuscript will be acknowledged by email. Every effort will be made to complete the review process within 3 weeks and communicated to the corresponding author. Papers should be submitted electronically on the journal's website. The Editorial Board will strive for the quality of the journal and will also index the journal in various indexing bodies and the information will be updated on the journal website from time to time. We welcome all your submissions. I hope you will consider IJCBR for your next submission. If any further information is required please mail to:</p> <p> <a href="http://localhost/sppp/index.php/index/admin/wizard/2/mailto:editor.ijcbr@gmail.com">Editor</a> and/or <a href="http://localhost/sppp/index.php/index/admin/wizard/2/mailto:journaloffice@sumathipublications.com">Journal Office</a>.</p> <p>The journal accepts manuscripts in the following forms:</p> <ul> <li class="show">Original research articles</li> <li class="show">Reviews</li> <li class="show">Case reports</li> <li class="show">Short communications</li> <li class="show">Letters to editor</li> <li class="show">Discussion papers</li> <li class="show">Clinical Experience</li> <li class="show">Clinicopathological correlation Book reviews and</li> <li class="show">"How to do it" type articles describing new methods or procedures.</li> </ul> <p>Kind regards,</p> <p>IJCBR Editorial Team.</p> Sumathi Publications en-US International Journal of Clinical and Biomedical Research 2521-0394 <p>The journal <strong>allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions</strong>.</p> <p>The submitted papers are assumed to contain no proprietary material unprotected by patent or patent application; responsibility for technical content and for protection of proprietary material rests solely with the author(s) and their organizations and is not the responsibility of the journal. The main (first/corresponding) author is responsible for ensuring that the article has been seen and approved by all the other authors. It is the responsibility of the author to obtain all necessary copyright release permissions for the use of any copyrighted materials in the manuscript prior to the submission.</p> <p><strong>What are my rights as an author?</strong><br>It is important to check the policy for the journal to which you are submitting or publishing to establish your rights as<br>Author. Journal's standard policies allow the following re-use rights:</p> <ul> <li class="show">The journal allows the author(s) to hold the copyright without restrictions.</li> <li class="show">The journal allows the author(s) to obtain publishing rights without restrictions.</li> <li class="show">You may do whatever you wish with the version of the article you submitted to the journal.</li> <li class="show">Once the article has been accepted for publication, you may post the accepted version of the article on your own personal website, your department's website or the repository of your institution without any restrictions.</li> <li class="show">You may not post the accepted version of the article in any repository other than those listed above (i.e. you may not deposit in the repository of another institution or a subject-matter repository) until 12 months after publication of the article in the journal.</li> <li class="show">You may use the published article for your own teaching needs or to supply on an individual basis to research colleagues, provided that such supply is not for commercial purposes.</li> </ul> Comparison of electromyographic activity of quadriceps muscle in persons with unilateral traumatic transtibial amputation using patellar tendon bearing supracondylar endoskeletal prosthesis with the unaffected limb in weight bearing positions. https://www.sumathipublications.com/index.php/ijcbr/article/view/402 <p><strong>Abstract</strong></p> <p><strong>Purpose: </strong>comparison of electromyographic activity of quadriceps muscle in persons with unilateral traumatic transtibial amputation using patellar tendon bearing supracondylar endoskeletal prosthesis with the unaffected limb in weight bearing positions.</p> <p><strong>Method: </strong>30 individuals<span class="Apple-converted-space">&nbsp; </span>aged 18-60 years were assessed using surface electromyography with functional level K3 according to K-level functional assessment scale to compare the activity of quadriceps of affected side using patellar tendon bearing supracondylar endoskeletal prosthesis with the unaffected side. The data was analysed using paired t-test.</p> <p><strong>Result</strong>:<span class="Apple-converted-space">&nbsp; </span>There was a significant difference in the activity of VMO and VLO muscles of the quadriceps in high sitting positions. There was also a significant difference in the activity of VMO muscle in single limb stance and bipedal stance. However, there was no significant difference between the activity of VLO muscle in bipedal stance but there was reduced activity of VLO muscle in the prosthetic limb in single limb stance.</p> <p><strong>Conclusion:</strong> The quadriceps activity was reduced in the affected limb in high sitting position, single<span class="Apple-converted-space">&nbsp; </span>limb stance and bipedal stance. However, no difference in the muscle activity was noted in VLO muscle in bipedal stance.</p> <p><strong>Keywords</strong>: <em>trans tibial amputation, patellar tendon bearing supracondylar prosthetis, surface electromyography.<span class="Apple-converted-space">&nbsp;</span></em></p> Dipti Naik Vaibhav Dolas Copyright (c) 2021 Dipti Naik, Vaibhav Dolas http://creativecommons.org/licenses/by-nc-sa/4.0 2021-05-04 2021-05-04 1 5 10.31878/ijcbr.2021.72.01 Myoinositol with Metformin and Myoinositol alone in infertile PCOS women undergoing ovulation induction cycles: A comparative study https://www.sumathipublications.com/index.php/ijcbr/article/view/412 <p>Background: This was a prospective observational study conducted over a twelve-month duration in our institute to compare the combined effect of metformin and myoinositol with metformin alone. Method: A total of sixty patients were included in the study, and they were divided into two groups depending on whether they were given the combination or the single drug. Group A (n=30) was given Myoinositol 600 mg+Metformin 500 mg thrice a day, and Group B ( n=30) was given only Myoinositol 600 mg thrice a day. The outcome measure was clinical pregnancy rate and improvement in clinical and hormonal parameters after drug therapy. Results: BMI (p&lt;0.01), modified Ferriman Gallaway score (p&gt;0.05), and the was a significant improvement in the hormonal parameters (LH,FSH) in both the groups and the levels were found to be comparable after a period of 6 months. The clinical pregnancy rate after six cycles of ovulation was significantly higher in Group A as compared to Group B. In Group A, the total clinical pregnancy rate was 43.33%, and in Group B, it was 26.67%, respectively, and the end of 6 months and the difference was statistically significant (p = &lt;0.01) Conclusion: Equal response in reduction of hormonal levels and clinical and laboratory parameters were seen in both groups, while better results in terms of clinical fertility rates were observed in the group that was given a combination of myoinositol with metformin.</p> Pramod Gade Aher Gautam S Vazifdar Sharmeen Copyright (c) 2021 Pramod Gade, Aher Gautam S, Vazifdar Sharmeen http://creativecommons.org/licenses/by-nc-sa/4.0 2021-05-04 2021-05-04 1 10 10.31878/ijcbr.2021.72.02