FEASIBILITY STUDY ON BLOOD CELL COUNTING USING MOBILE PHONE-BASED PORTABLE MICROSCOPE

Waliullah A S M

Abstract


Objectives: To check the feasibility of using the mobile phone-based microscope for blood cell counting from human blood histological sample. Methodology: A feasibility study was performed by imaging blood histology samples with one novel type of microscope “Foldscope” and image compared with a conventional microscope in the laboratory facility. The image acquired from both modalities were processed further and compared and analyzed. Results: Mobile phone-based microscope acquired images were observed and compared with a conventional microscope and found the blood cell counting feasibility and morphology analysis of the blood histology sample were significantly similar as of conventional light microscope images. Conclusion: By comparing the image from both microscopes, it could be stated that this method is feasible for human blood histopathological sample investigations like blood cell counting and morphology analysis especially in the low resource area or in case of any emergency situations.

 


Full Text:

PDF

References


Breslauer DN, Maamari RN, Switz NA, Lam WA, Fletcher DA. Mobile phone based clinical microscopy for global health applications. PLoS One. 2009;4(7):e6320.

Bogoch, II, Koydemir HC, Tseng D, Ephraim RKD, Duah E, Tee J, et al. Evaluation of a Mobile Phone-Based Microscope for Screening of Schistosoma haematobium Infection in Rural Ghana. Am J Trop Med Hyg. 2017;96(6):1468-71.

Pirnstill CW, Cote GL. Malaria Diagnosis Using a Mobile Phone Polarized Microscope. Sci Rep-Uk. 2015;5.

Waliullah A. Application Of Mobile Phone-Based Portable Microscopy In Clinical Histopathology: A Feasibility Study. International Journal of Clinical and Biomedical Research (IJCBR). 2018;4(2):16-20.

Cybulski JS, Clements J, Prakash M. Foldscope: origami-based paper microscope. PLoS One. 2014;9(6):e98781.

Turgeon ML. Clinical hematology: theory and procedures: Lippincott Williams & Wilkins; 2005.

Uhm TG, Kim BS, Chung IY. Eosinophil development, regulation of eosinophil-specific genes, and role of eosinophils in the pathogenesis of asthma. Allergy, asthma & immunology research. 2012;4(2):68-79.

Niemiec MJ, De Samber B, Garrevoet J, Vergucht E, Vekemans B, De Rycke R, et al. Trace element landscape of resting and activated human neutrophils on the sub-micrometer level. Metallomics. 2015;7(6):996-1010.

Shaw PA, Friedman ES. Clinico‐Histologic Conferences: Histology and disease. Anatomical sciences education. 2012;5(1):55-61.

Petti CA, Polage CR, Quinn TC, Ronald AR, Sande MA. Laboratory medicine in Africa: a barrier to effective health care. Clinical Infectious Diseases. 2006;42(3):377-82.

Linder E, Grote A, Varjo S, Linder N, Lebbad M, Lundin M, et al. On-chip imaging of Schistosoma haematobium eggs in urine for diagnosis by computer vision. PLoS Negl Trop Dis. 2013;7(12):e2547.

Hartman DJ, Parwani AV, Cable B, Cucoranu IC, McHugh JS, Kolowitz BJ, et al. Pocket pathologist: A mobile application for rapid diagnostic surgical pathology consultation. J Pathol Inform. 2014;5(1):10.




DOI: https://doi.org/10.31878/ijcbr.2018.43.16

Article Statistics:

Abstract 23 PDF 7

Refbacks

  • There are currently no refbacks.




Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.